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Entresto

Entresto Used For: A Comprehensive Guide

Entresto is a prescription medication widely recognized for its role in managing heart failure. This article explores the specific uses of Entresto, how it works, and what patients need to know when prescribed this medication.

What is Entresto?

Entresto is a combination drug containing sacubitril and valsartan. Sacubitril works by inhibiting the enzyme neprilysin, leading to the relaxation of blood vessels and a reduction in the strain on the heart. Valsartan, an angiotensin II receptor blocker (ARB), helps lower blood pressure by preventing blood vessels from narrowing. Together, these components make Entresto an effective treatment for heart failure.

Entresto Used For: Heart Failure Management

Entresto is primarily used to treat certain types of heart failure, particularly chronic heart failure with reduced ejection fraction (HFrEF). This condition occurs when the heart muscle is weakened and cannot pump blood efficiently, leading to symptoms like shortness of breath, fatigue, and fluid retention. Entresto is prescribed to:

  • Improve Survival Rates: Clinical studies have shown that Entresto reduces the risk of death from cardiovascular causes in patients with HFrEF.
  • Reduce Hospitalizations: By managing the symptoms and underlying causes of heart failure, Entresto helps lower the likelihood of hospital admissions due to heart failure exacerbations.
  • Enhance Quality of Life: Patients taking Entresto often experience improved exercise tolerance and a better overall quality of life.

How to Take Entresto

Entresto is typically taken twice daily, with or without food. The dosage will vary based on individual patient needs, including their kidney function and any other medications they may be taking. It’s crucial to follow the prescribing doctor’s instructions and not to adjust the dose without medical guidance.

Potential Side Effects

Like all medications, Entresto can cause side effects. Common side effects include:

  • Low Blood Pressure (Hypotension): Patients may feel lightheaded or dizzy, especially when standing up quickly.
  • Elevated Potassium Levels (Hyperkalemia): This can lead to dangerous heart rhythms if not monitored.
  • Kidney Problems: Entresto may cause or worsen kidney issues in some patients.

It’s important to discuss any side effects with a healthcare provider. They can help manage or mitigate these effects, ensuring the treatment’s benefits outweigh the risks.

Precautions and Considerations

Before starting Entresto, patients should inform their healthcare provider of any other medical conditions or medications they are taking, including over-the-counter drugs and supplements. Specific precautions include:

  • Pregnancy and Breastfeeding: Entresto should not be used during pregnancy due to the risk of harm to the unborn baby. It’s also recommended to avoid breastfeeding while taking this medication.
  • Drug Interactions: Entresto can interact with other medications, such as ACE inhibitors, ARBs, and certain diuretics. It’s crucial to have a healthcare provider review all medications to prevent adverse interactions.

Entresto is a significant advancement in the treatment of heart failure, offering patients improved survival rates, fewer hospitalizations, and a better quality of life. If you or a loved one has been prescribed Entresto, understanding its uses and potential effects can help you manage heart failure more effectively.

For more detailed information about Entresto, visit Used For to learn more about its applications. Additionally, you can explore authoritative sources like the American Heart Association for further reading on heart failure treatments.


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